When delivering instruction for students with disabilities, teachers should consider a three-phase cycle of plan, deliver, review and intensify individual, small-group, and whole-group instruction. This brief focuses on delivering instruction using a model of explicit instruction. Explicit instruction is a combination of modeling and practice that research has shown to benefit the teaching of reading, writing, and mathematics and has been found to be especially beneficial when teaching students with disabilities. The brief highlights what teachers need to know about the practice, the delivery of instruction for students with disabilities, how the practice can be used to support access to the general education classroom, and how to get started delivering instruction. Delivering instruction includes multiple high-leverage practices for students with disabilities including using explicit instruction and providing positive and constructive feedback to guide students' learning and behavior.